Chapter 11: Diabetic ketoacidosis and hyperglycemic hypersmolar state
Moderator(s): David Maahs
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12/14/2017 at 9:47:12 AM GMT
Posts: 10
Chapter 11: Diabetic ketoacidosis and hyperglycemic hypersmolar state

Dear ISPAD member/friend,

The 2014 ISPAD Practical Consensus Guidelines were much appreciated. We are happy to announce that preparations for the 2018 Guidelines are now well underway and that a new draft chapter is now ready for your comments and input. We look forward to hearing your thoughts and ideas on the Diabetic ketoacidosis and hyperglycemic hypersmolar state chapter here below!

Kind regards,

David Maahs
ISPAD Secretary-General

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12/19/2017 at 1:08:23 AM GMT
Posts: 3
Congratulations on this important body of work and many thanks for including the updated PECARN data. This is a significant addition to the field.

Under the section that deals with the complication of cognitive impairment (page 43), may I suggest adding in the more recent work by Shehata et al J Child Neurol 2010; 25:469-74 showing that DKA impacted on many more cognitive domains other than just memory, and our prospective studies (Nadebaum et al Pediatr Diabetes 2012; 13:632-7, and Cameron et al Diabetes Care 2014; 37:1554-62) showing the importance of altered mental state and subclinical grey/white matter volume changes at diagnosis as predictors of subsequent cognitive function in the medium term.


Fergus Cameron

1/6/2018 at 3:16:06 PM GMT
Posts: 4

Thank you for your comments. I will amend the article to include effects of DKA on other cognitive domains and grey/white matter changes. JW

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