Excellent, comprehensive coverage of this topic!
Some comments and suggestions for the authors' consideration
Page 4 bullet 3
Highlight that this should be a FASTING lipid profile? 3aii (1) states fasting
Page 7 2nd line from bottom of page: typo ethnic/racial
Page 8 so as not to offend our Canadian colleagues, include Canadian First Nation youth in the list of high risk populations
Page 9 3rd line from bottom of page typo: autoimmune-mediated T1D
Page 9 The most recent report from SEARCH for Diabetes in Youth study indicated that in youth with T2D, DKA at presentation decreased from 11.7% 2002-2003 to 5.7% in 2008-2010. Dabelea, D et al Pediatrics 2014;133(4):e938-45
Page 10 Because measurement of diabetes autoantibodies may not be available or cost may be prohibitive, one us has to rely on clinical criteria. The article by Julia von Oettingen in Pediatric Diabetes 2016;17(6):416-425 provides a simple clinical scoring system (weight Z-score, age and race) that may be useful in these circumstances (low resource settings).
Page 11 … as the insulin resistance of puberty wanes
Page 24 Indicate whether the goals levels refer to fasting or non-fasting samples… or does it matter? Fasting samples more difficult to obtain in clinical practice. May require patent returning to clinic on another day and this adds to the patient’s burden (inconvenient, cost of travel, time off work, missed school, etc.).