This website uses cookies to store information on your computer. Some of these cookies are used for visitor analysis, others are essential to making our site function properly and improve the user experience. By using this site, you consent to the placement of these cookies. Click Accept to consent and dismiss this message or Deny to leave this website. Read our Privacy Statement for more.
JENIOUS Research Projects - Call for Applications
Group HomeGroup HomeGroup PagesDirectory & Features Join Group
Call for Applications - June 2018

The Effect of Frequent Continuous Glucose Monitoring Use on Glucose Variability in Preschoolers With Type 1 Diabetes
– The VibRate study


Final version 3. Jan. 2018, after JENIOUS discussion meeting in Innsbruck on October 22, 2017


Glucose variability (GV) is potentially associated with damage to the developing brain in children with type 1 diabetes (T1D). Regular continuous glucose monitoring (CGM) use reduces GV in older children. The evidence on CGM efficacy in preschool children is limited and inconsistent. The objective of this study is to evaluate the efficacy of CGM on GV in preschoolers with T1D.

Research Questions:
To evaluate the effect of CGM use on glucose variability (primary endpoint) and other metrics of glycemic control (secondary endpoint) in population of children with type 1 diabetes below 7 years on CSII therapy (for at least 6 months).

Primary contact person

Klemen Dovc:


Study details (eligibility criteria, center information (no. of patients, HCPs, ), template spreadsheet, etc.) will be send subsequently.


Requirements for participation of countries:
Center data available for whole observational period (1 year, expected July 2018 – June 2019)
No obvious selection bias
Willingness to share patient-level data for joint analysis


Required Data per Patient (T1D only)
Gender (M / F)
Body weight, body height
Date of birth
Date of T1D onset
Date of CSII therapy onset
CSII model
Date of CGM onset
CGM model
C-peptide (if applicable)

For each visit:
Sensor and Pump downloads (saved preferably as CSV/XLS or TXT format; eventually as PDF)
Basal/Bolus ratio
Mean (SD) Blood Glucose
Mean (SD) Sensor Glucose
DKA/Severe hypoglycemia events

Commitment to participate until 30. June 2018
Study end June 2019 
Preliminary statistical analysis until September 2019
First draft of manuscript end of 2019

Contact Us

ISPAD Executive Office
c/o K.I.T. Group GmbH
Association & Conference Management
Kurfürstendamm 71
10709 Berlin, Germany


Click the link below to join the Society!

Join Today!

Phone: +49 (0)30 24603-210
Fax: +49 (0)30 24603-200
Email: secretariat@ispad.or

Privacy Policy
Terms of Service
Legal Notice    


 © 2020 International Society for Pediatric and Adolescent Diabetes (ISPAD)

Association Management Software Powered by YourMembership  ::  Legal