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Ch 1: Definition, epidemiology, diagnosis and classification of Diabetes in Children and Adolescents

Chapter 1: Definition, epidemiology, diagnosis and classification of Diabetes in Children and Adolescents

 
Elizabeth J. Mayer-Davis, Anna R. Kahkoska, Craig Jefferies, Dana Dabelea, Naby Balde, Chun Xiu Gong, Pablo Aschner, Maria E. Craig

 

Chapter highlights:

•    Emerging evidence suggests that trends in incidence of type 1 diabetes vary markedly from country-to-country


•    
Although type 1 diabetes accounts for the majority of childhood and adolescent diabetes, the worldwide incidence and prevalence of type 2 diabetes in children and adolescents is increasing. Population-based epidemiologic data is limited and suggests that patterns of incidence vary by country, age category, and racial/ethnic subgroups.


•    Recent genome wide association and whole genome/exome sequencing studies have increased clinical understanding of monogenic forms of diabetes that are distinct from the major classes of type 1 and type 2 diabetes.

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